Knicks vs Celtics Picks and Prediction – 5/5/2025

In the first game of a Monday night NBA on TNT playoff doubleheader, the New York Knicks will invade TD Garden to take on the Boston Celtics. For other NBA action see our NBA Predictions. The third-seeded Knicks are undefeated through their first three road playoff games and are making their third consecutive Eastern Conference Semifinal appearance. On Thursday, All-Star G Jalen Brunson nailed a three-pointer with 4.3 seconds remaining to lift New York to a 116-113 road victory against Detroit. 

Brunson finished with a game-high 40 points on 15-for-33 shooting and dished out seven assists. New York G/F Mikal Bridges chipped in 25 points (11-16 FG) and four boards. OG Anunoby added 22 points and five rebounds for the Knicks, who shot 48 percent from the field. 

The Boston Celtics have reached the NBA Finals in two of the last three seasons and are in search of their NBA record 19th title. The second-seeded Celtics have won their first three home games this postseason and rank second in defensive efficiency. On Tuesday, Boston assisted on 30 of 43 made field goals and shot a sizzling 57 percent overall during a 120-89 home victory versus Orlando. 

All-Star F Jayson Tatum poured in a game-high 35 points (10-16 FG) to go along with ten assists and eight rebounds. All-Star G Jaylen Brown contributed 23 points (9-18 FG) and six boards. Payton Pritchard was impactful with ten points and a plus 29 rating in 25 minutes off the bench for the Celtics. 

Boston G Jrue Holiday (hamstring) was a full participant in Saturday’s practice and is expected to play in the series opener. The Celtics swept the Knicks in four meetings this season and averaged 125 points, so the over is worth a look. Take a healthy and New York squad to steal the opener on the road. Final Score Prediction, New York Knicks win 110-107.