Pistons vs Knicks Picks and Prediction – 4/29/2025

By: Eddie Kline |

Last Updated: 04/27/2025 at 9:01 PM ET

Detroit Pistons at New York Knicks 04/29/25 - NBA Picks & Predictions
Game Start: 4/29/2025, 11:30 PM UTC
Latest Odds: NYK -5.5 ; O/U 212.5

Pistons vs Knicks Prediction

The Detroit Pistons will look to stave off elimination on Tuesday night, when they travel to Madison Square Garden to battle the New York Knicks. For other NBA action see our NBA Predictions. Despite outplaying the Knicks for much of this series, the sixth-seeded Pistons (1-3) were unable to win a home playoff game for the first time since 2008. In Game Four, Detroit missed 22 of 29 three-point attempts and was unable to protect an 11-point second half lead during a crushing 94-93 home loss.

All-Star G Cade Cunningham recorded the third triple-double in Detroit playoff history with 25 points, ten rebounds, and ten assists. Veteran F Tobias Harris added 18 points on 6-for-15 shooting and grabbed eight rebounds. Tim Hardaway Jr. missed a three-point attempt as time expired and finished with 14 points for the Pistons. 

The New York Knicks won 27 of their 41 home games during the regular season and are looking to make their third consecutive appearance in the Eastern Conference semifinals. The third-seeded Knicks (3-1) rank fifth in this postseason in offensive efficiency and are averaging 107.3 points per game. During Sunday’s road victory, New York connected on 15-of-33 from the three-point line.  

All-Star G Jalen Brunson tallied a game-high 32 points (13-26 FG), 11 assists, and five rebounds. All-Star F/C Karl-Anthony Towns nailed two big shots in the final few minutes and finished with 27 points. Josh Hart added 14 points, ten rebounds, and five assists for the Knicks. 

Pistons vs Knicks Pick Analysis

Detroit C Isaiah Stewart has missed the last three games with knee inflammation and his status for this contest is uncertain. The Pistons have revived their fan base, but their lack of playoff experience has shown throughout this series. Take the Knicks to close things out at home with a cover. Final Score Prediction, New York Knicks win 113-99. 

Our Free NBA Pick for New York Knicks vs Detroit Pistons

New York Knicks -5.5