Cavaliers vs Pacers Picks and Prediction – 4/10/2025

By: Eddie Kline |

Last Updated: 04/09/2025 at 6:47 PM ET

Cleveland Cavaliers at Indiana Pacers 04/10/25 - NBA Picks & Predictions
Game Start: 4/10/2025, 11:00 PM UTC
Latest Odds: IND -8.5 ; O/U 230.5

Cavaliers vs Pacers Prediction

In the first game of a Thursday night NBA on TNT doubleheader, the Cleveland Cavaliers will square off against the Indiana Pacers from Gainbridge Fieldhouse. For other NBA action see our NBA Predictions. The Cavaliers (63-16) have won 29 of their 39 road games and have clinched the top seed in the Eastern Conference. On Tuesday, Cleveland connected on half of their 50 three-point attempts during a 135-113 home victory versus Chicago. 

All-Star G Darius Garland led all scorers with 28 points on 10-for-17 shooting and dished out five assists. All-Star F Evan Mobley contributed 21 points, 12 rebounds, and seven assists. Ty Jerome added 18 points and five assists off the Cleveland bench. 

The Indiana Pacers are riding a five-game winning streak and trail New York by two games for third place in the Eastern Conference standings. The Pacers (48-31) rank sixth in the league in offensive efficiency and are averaging 117.3 points per contest. On Tuesday, Indiana overcame a cool 38 percent shooting night to earn a 104-98 home victory versus lowly Washington.

All-Star F Pascal Siakam tallied a game-high 24 points on 11-for-19 shooting and grabbed ten rebounds. Indiana G Tyrese Haliburton chipped in 22 points (9-11 FT) and six assists. Myles Turner added 14 points and 11 rebounds for the Pacers, who improved to 28-11 at home. 

Cavaliers vs Pacers Pick Analysis

Cleveland G Donovan Mitchell sat out on Tuesday due to an ankle sprain and is considered day-to-day. The Cavaliers are unlikely to catch Oklahoma City for the best record in the league and the Pacers still have a shot at catching the Knicks. Take Indiana to win at home. Final Score Prediction, Indiana Pacers win 123-114.

Our Free NBA Pick for Indiana Pacers vs Cleveland Cavaliers

Indiana Pacers -8.5