Nationals vs Mariners Picks and Prediction – 5/29/2025

The Washington Nationals are heading to T-Mobile Park on Wednesday, where they will matchup against the Seattle Mariners. Get the rest of our free MLB picks here! The Nationals come into this game with a 24-29 record which places them fourth in the NL East. Washington has dropped two of their last three games, as they are coming off a 3-2 loss against the Giants. Trevor Williams  is set to be the Nationals starting pitcher in this game, he’s posted a 6.39 ERA to go along with his 2-5 record.

The Seattle Mariners are the number one team in the AL West, putting together a record of 29-23. The Mariners have now dropped two straight games, most recently suffering a 5-3 loss against the Houston Astros on Sunday. George Kirby is set to be the Mariners’ starting pitcher in this game, he’s posted a 12.27 ERA through just 3.2 innings of play this season. Seattle is scoring 4.7 runs per game, while giving up 4.2 runs a game defensively.

The Mariners head home where they look to avoid their third straight loss, while the Nationals also hope to bounce back after a loss to San Francisco. Expect Seattle to get the job done in their home park, as they cover the -1.5 spread. Final score prediction,  Seattle wins 5-3.