Nationals vs Padres Picks and Prediction – 6/25/2025

Beautiful Petco Park will play host to a Wednesday afternoon MLB clash between the Washington Nationals and the San Diego Padres. Be ready for the baseball season with all of our MLB predictions. The Nationals (33-47) have dropped eight of their previous 11 games and have fallen into the NL East Division basement. Last night, Washington batters went 1-for-9 with runners in scoring position and left eight men on base during a 4-3 road loss against San Diego. 

Twenty-six year old southpaw MacKenize Gore (3-7 3.19 ERA) will head to the hill for the Nationals in this contest. Through 93 innings of work, Gore ranks second in the majors with 123 strikeouts and owns a solid 1.19 WHIP.

The San Diego Padres have won 24 of their first 38 home games and are five games out of first place in the NL West Division. During Tuesday’s home victory, San Diego 1B Luis Arraez went 2-for-4 and scored a run. Closer Robert Suarez pitched a perfect ninth inning to notch his 22nd save for the Padres, who improved to 43-36 overall. 

San Diego skipper Mike Shildt will turn to talented right-hander Nick Pivetta (7-2 3.64 ERA) in the series finale. Last time out, Pivetta (4.2 IP) gave up six hits and four runs during a 6-5 home loss versus Kansas City. 

Washington C Keibert Ruiz exited Monday’s game with an apparent head injury and is listed as day-to-day. Through 80 games, Washington ranks 18th in OPS and 14th in runs scored. For the season, San Diego ranks 22nd in OPS and 18th in runs scored. Take the Nationals to win on the road. Final Score Prediction, Washington Nationals win 4-3.