Nationals vs Padres Picks and Prediction – 6/25/2025

By: Anthony Allen |

Last Updated: 06/23/2025 at 11:02 PM ET

Washington Nationals at San Diego Padres 06/24/25 - MLB Picks & Predictions
Game Start: 6/25/2025, 1:40 AM UTC
Latest Odds: SDP -165 ; O/U 8.5

Nationals vs Padres Prediction

The Washington Nationals will be returning to Petco Park on Tuesday, where they will take on the San Diego Padres. Get the rest of our free MLB picks here! The Nationals are 32-46 and are ranked 25th according to ESPN in the late June rankings. The Nationals have struggled playing against the Padres as they are 0-6 in the last six games they played against them. Trevor Williams is headed to the mound for the Nationals in this game, he is 3-8 with a 5.54 ERA and a 1.45 whip. The Nationals have the 29th ranked bullpen so far this season. James Wood leads the Nationals this year with 21 home runs and 57 RBI. The Nationals are 2-3 in their last five games played.

The San Diego Padres are ranked 10th according to ESPN in the late June rankings. The Padres have won the last six games they played against Washington. Ryan Bergert will be San Diego’s starting pitcher on Tuesday, he is 0-0 with a 1.88 ERA so far this season. San Diego has the 5th ranked bullpen up till now this year. Manny Machado leads the Padres this season with a .305 batting average, 12 home runs and 46 RBI. The Padres are 3-2 in their last five games played. 

Nationals vs Padres Pick Analysis

The San Diego Padres have dominated this Washington Nationals team beating them in the last six games, and beating them by more than two runs in five of those games. The Padres have been winning more lately than the Nationals and are very good at Petco Park. The Padres will get the job done here on Tuesday night. Final Score Prediction, San Diego Padres win 5-3. 

Our Free MLB Pick for San Diego Padres vs Washington Nationals

San Diego Padres -1.5