Nationals vs Padres Picks and Prediction – 6/24/2025

By: David Anicetti |

Last Updated: 06/22/2025 at 9:47 PM ET

Washington Nationals at San Diego Padres 06/23/25 - MLB Picks & Predictions
Game Start: 6/24/2025, 1:40 AM UTC

Nationals vs Padres Prediction

The Washington Nationals open a three-game series on the road Monday versus the San Diego Padres. Washington improved to 32-45 following Saturday’s 7-3 victory over the Los Angeles Dodgers. Washington has won two of the last three since snapping an 11-game losing streak. Washington trails first-place co-leaders New York and Philadelphia in the National League East by 14 games. Keep up to date with all the MLB action with our expert MLB picks.

James Wood is batting .278 with 21 home runs, 57 RBI, 81 hits, and an on-base percentage of .375 to lead Washington in each of the five categories. Nathaniel Lowe is second in home runs with 12. Washington is batting .240 with a .391 slugging percentage. On Monday, Washington will send Mitchell Parker to the mound. The left-hander is 4-8 with a 4.59 ERA, 58 Ks, and 31 BBs.

The San Diego Padres improved to 41-35 following Saturday’s 5-1 victory over the Kansas City Royals. Fernando Tatis Jr hit a three-run home run, and Dylan Cease allowed just three hits while pitching into the 7th inning. San Diego has won two of the last three. The Padres trail the first-place Los Angeles Dodgers by five games in the National League West.

Manny Machado is batting .309 with 46 RBI, 89 hits, and an on-base percentage of .373 to lead San Diego in the four categories. Fernando Tatis Jr leads in home runs with 14. San Diego is batting .250 with a .381 slugging percentage. On Monday, the San Diego Padres will send Stephen Kolek to the mound. The right-hander is 3-2 with a 3.59 ERA, 37 Ks, and 19 BBs.

Nationals vs Padres Pick Analysis

San Diego will win at home on Monday when hosting Washington, but the play here is OVER. The OVER has cashed in four of Washington's last six and four of San Diego's last six played at home. Washington starter Mitchell Parker has allowed a total of seven runs on 18 hits across 15.1 innings, but six runs were in one outing. San Diego starter Stephen Kolek has allowed seven runs on 13 hits across the last 10.2 innings. Final Score Prediction: San Diego Padres win but our best play is OVER 8-5.

Our Free MLB Pick for San Diego Padres vs Washington Nationals

Over