Nationals vs Pirates Picks and Prediction – 4/14/2025

By: Eddie Kline |

Last Updated: 04/13/2025 at 8:22 PM ET

Washington Nationals at Pittsburgh Pirates 04/14/25 - MLB Picks & Predictions
Game Start: 4/14/2025, 10:40 PM UTC
Latest Odds: PIT -210 ; O/U 7

Nationals vs Pirates Prediction

The Monday MLB schedule will get underway with a matchup between the Washington Nationals and the Pittsburgh Pirates from PNC Park. Be ready for the baseball season with all of our MLB predictions. The Nationals (6-9) have dropped five of their first six road games and have given up a National League worst 80 runs. On Sunday, three Washington relievers surrendered seven runs and recorded just six outs during an 11-4 road loss against Miami. 

Washington manager Dave Martinez has yet to announce a starting pitcher for the series opener. The Nationals rank near the bottom of the majors with a 4.68 team ERA and an alarming 1.50 WHIP.

The Pittsburgh Pirates have scored just 50 runs through their first 16 games and are trapped in the NL Central Division basement. On Sunday, Pittsburgh batters were limited to two hits and struck out nine times during a 4-0 road loss against Cincinnati. SP Carmen Mlodzinski (1-2) gave up four runs in four plus innings and took the loss for the Pirates (5-11), who fell to 2-8 on the road. 

National League Rookie of the Year Paul Skenes (1-1 3.44 ERA) is off to a solid start for the Pirates. Through 18 plus innings, Skenes has yet to allow a home run and struck out 20 batters while posting a minuscule 0.83 WHIP.

Nationals vs Pirates Pick Analysis

Pittsburgh SP Jared Jones (elbow) has been transferred to the 60-day injured list and is not expected to make his season debut until July. Through 15 games, Washington ranked 16th in OPS and 12th in runs scored. For the regular season, Pittsburgh ranked 30th in OPS and 24th in runs scored. Take the under. Final Score Prediction, Pittsburgh Pirates win 4-1.

Our Free MLB Pick for Pittsburgh Pirates vs Washington Nationals

UNDER 7