Blue Jays vs Guardians Picks and Prediction – 6/26/2025

By: Eddie Kline |

Last Updated: 06/25/2025 at 10:02 PM ET

Toronto Blue Jays at Cleveland Guardians 06/26/25 - MLB Picks & Predictions
Game Start: 6/26/2025, 5:10 PM UTC
Latest Odds: CLE -115 ; O/U 9

Blue Jays vs Guardians Prediction

In Thursday afternoon MLB action, the Toronto Blue Jays and the Cleveland Guardians will wrap up their series from Progressive Field. Be ready for the baseball season with all of our MLB predictions. The Blue Jays (42-37) are four games below .500 on the road and are three games out of first place in the AL East Division. Last night, Toronto 1B Vladimir Guerrero Jr. homered and scored a pair of runs during a 5-4 road loss in ten innings. 

Thirty-four year old righty Kevin Gausman (5-6 4.60 ERA) will take the mound for the Blue Jays in this matchup. In his last start, Gausman (4.1 IP) was tagged for seven hits and seven runs during a 9-5 home loss versus Arizona. 

The Cleveland Guardians have split their previous ten games and trail AL Central Division leading Detroit by 8.5 games. On Wednesday, Cleveland walked it off on a Jose Ramirez single that scored pinch-runner Angel Martinez with the winning run. OF Lane Thomas went 2-for-4 with a solo shot for the Guardians (40-38), who moved their home record to 20-18. 

Cleveland manager Stephen Vogt will give the nod to right-hander Tanner Bibee (4-7 3.86 ERA) on Thursday. The Guardians have dropped four of Bibee’s last five starts and he has allowed 16 runs (15 ER) over his last 30 plus innings. 

Blue Jays vs Guardians Pick Analysis

Toronto OF Anthony Santander (shoulder) has yet to resume hitting and remains without a timetable to return. Through 79 games, Toronto ranks 12th in OPS and 15th in runs scored. For the season, Cleveland ranks 26th in OPS and 25th in runs scored. Take the under. Final Score Prediction, Cleveland Guardians win 4-3. 

Our Free MLB Pick for Cleveland Guardians vs Toronto Blue Jays

UNDER 9