Rays vs Padres Picks and Prediction – 4/26/2025

By: Anthony Allen |

Last Updated: 04/24/2025 at 9:43 PM ET

Tampa Bay Rays at San Diego Padres 04/25/25 - MLB Picks & Predictions
Game Start: 4/26/2025, 1:40 AM UTC
Latest Odds: SDP -284 ; O/U 7

Rays vs Padres Prediction

The Tampa Bay Rays will be returning to Petco Park on Friday, where they will take on the San Diego Padres. Get the rest of our free MLB picks here! The Tampa Bay Rays are ranked 12th according to ESPN in the early April rankings. Tampa Bay is 1-4 over the last five games played against San Diego. Shane Baz is headed to the mound for the Rays in this game, he won his last start against San Diego and has been good so far this season. Tampa Bay has the 17th ranked bullpen so far this season. Jonathan Aranda leads the Rays this season with a .344 batting average and 13 RBI. The Rays are 2-3 in their last five games played.

The San Diego Padres are ranked 1st according to ESPN in the early April rankings. The Padres are 4-1 in their last five games they played against Tampa Bay. Michael King will be San Diego’s starting pitcher on Friday, he is 3-0 with a 2.57 ERA so far this season. San Diego has the 1st ranked bullpen up till now this year. Fernando Tatis Jr leads the Padres this season with a .344 batting average, 8 home runs and 17 RBI. The Padres are 2-3 in their last five games played. 

Rays vs Padres Pick Analysis

The Tampa Bay Rays are 1-4 away from home this year. The Rays have struggled against San Diego only winning one game in the last five games played against the Padres. San Diego is 12-1 at home and will have Michael King on the mound who has pitched well so far this season. The Padres will out score the Rays and get the job done at home on Friday night. Final Score Prediction, San Diego Padres win 4-2. 

Our Free MLB Pick for San Diego Padres vs Tampa Bay Rays

San Diego Padres