Rays vs Astros Picks and Prediction – 6/1/2025

By: David Anicetti |

Last Updated: 05/31/2025 at 9:09 PM ET

Tampa Bay Rays at Houston Astros 06/01/25 - MLB Picks & Predictions
Game Start: 6/1/2025, 6:10 PM UTC
Latest Odds: HOU -210 ; O/U 7.5

Rays vs Astros Prediction

The Tampa Bay Rays conclude a four-game series on the road Sunday versus the Houston Astros. Tampa Bay dropped to 29-28 following Friday’s 2-1 loss to the Astros in the second game of this series after opening the series with 13-3 on Thursday. Tampa Bay is second in the American League East, 6 ½ games behind the first-place New York Yankees. Keep up to date with all the MLB action with our MLB picks.

Jonathan Aranda is batting .322 with 55 hits and an on-base percentage of .409 to lead Tampa Bay in the three categories. Brandon Lowe is the leader in home runs with 11, and Junior Caminero is the leader in RBI with 32. Tampa Bay is batting .245 with a .379 slugging percentage. On Sunday, Tampa Bay will send Taj Bradley to the mound. The right-hander is 4-4 with a 4.38 ERA, 54 Ks, and 25 BBs.

The Houston Astros improved to 31-26 following Friday’s one-run win over the Tampa Bay Rays. Yainer Diaz hit a walk-off home run in the bottom of the ninth inning with two outs to give Houston the win over the Rays. Framber Valdez pitched a three-hitter for the Astros. Houston leapfrogged the Seattle Mariners into first place by a half-game in the American League West.

Jeremy Pena is batting .300 with 65 hits and an on-base percentage of .364 to lead Tampa Bay in the three categories. Isaac Paredes is the leader in home runs with 11 and RBI with 32. Houston is batting .255 with a .394 slugging percentage. On Sunday, the Houston Astros will send Hunter Brown to the mound. The right-hander is 7-3 with a 2.00 ERA, 79 Ks, and 16 BBs.

Rays vs Astros Pick Analysis

Tampa Bay has won eight of its last 10 and will have a starter on the mound who performed well against Houston last time out. Tampa Bay starter Taj Bradley has had two consecutive solid outings, allowing four runs on nine hits across 13 innings, which included an 8-4 win over the Astros. Houston starter Hunter Brown was hit hard by Tampa Bay on May 21, allowing five runs on seven hits across five innings. Final Score Prediction: Tampa Bay Rays win 5-2.

Our Free MLB Pick for Houston Astros vs Tampa Bay Rays

Tampa Bay Rays +190