Rays vs Orioles Picks and Prediction – 6/28/2025

In Saturday afternoon MLB action, the Tampa Bay Rays will take on the Baltimore Orioles from beautiful Camden Yards. Be ready for the baseball season with all of our MLB predictions. The Rays (46-36) have won seven of their last 11 games and trail AL East Division leading New York by 1.5 games. Last night, Tampa Bay 2B Brandon Lowe went 3-for-4 with four RBIs and a pair of runs scored during a 22-8 road loss against Baltimore. 

Twenty-nine year old righty Zack Littell (6-7 3.78 ERA) will head to the hill for the Rays in this contest. Tampa Bay has lost Littell’s previous three starts and he has given up eight runs over his last 17 innings. 

The Baltimore Orioles are three games below .500 at home and are trying to find their way out of the AL East Division basement. During Friday’s home victory, C Gary Sanchez’s two-run blast helped Baltimore overcome an early 6-0 deficit. OF Ramon Laureano reached base four times and scored four runs for the Orioles (35-46).

The Orioles will need more from thirty-one year old righty Zach Eflin (6-4 5.46 ERA) to climb back into contention. Last time out, Eflin (3 IP) was roughed up for ten hits and six runs during a 9-0 road loss against New York. 

Baltimore 1B Ryan Mountcastle has been diagnosed with a Grade 2 right hamstring strain and will be sidelined until August. Through 82 games, Tampa Bay ranks 8th in OPS and 6th in runs scored. For the season, Baltimore ranks 23rd in OPS and 24th in runs scored. Take the Rays to win on the road. Final Score Prediction, Tampa Bay Rays win 6-3.