Rays vs Orioles Picks and Prediction – 6/27/2025

Beautiful Camden Yards will play host to a Friday night MLB clash between the Tampa Bay Rays and the Baltimore Orioles. Be ready for the baseball season with all of our MLB predictions. The Rays (46-35) have won three straight games and trail AL East Division leading New York by a half-game. On Thursday, SP Shane Baz (8-3) fanned nine batters and lasted eight innings to lead Tampa Bay to a 4-0 road victory against Kansas City. 

Twenty-seven year old righty Ryan Pepiot (5-6 3.04 ERA) will take the mound for the Rays in this matchup. Through 94 plus innings, Pepiot has struck out 91 batters and sports a solid 1.10 WHIP.

The Baltimore Orioles have dropped six of their previous ten games and are struck in the AL East Division basement. On Wednesday, Baltimore batters were held hitless for the first seven innings of a 7-0 home loss versus Texas. SP Brandon Young (0-2) surrendered four runs in four innings and took the loss for the Orioles (34-46), who fell to 17-21 at home. 

Thirty-five year old righty Tomoyuki Sugano (5-4 3.55 ERA) has been a solid addition to the Baltimore rotation. Last time out, Sugano (3.2 IP) gave up seven hits and three runs during a 5-3 road victory against New York. 

Baltimore 1B Ryan Mountcastle has been diagnosed with a Grade 2 right hamstring strain and will be sidelined until August. Through 81 games, Tampa Bay ranks 11th in OPS and 8th in runs scored. For the season, Baltimore ranks 23rd in OPS and 24th in runs scored. Take the under. Final Score Prediction, Tampa Bay Rays win 5-2.