Rays vs Diamondbacks Picks and Prediction – 4/23/2025

By: Jeremy O’Quinn |

Last Updated: 04/21/2025 at 10:10 PM ET

Tampa Bay Rays at Arizona Diamondbacks 04/22/25 - MLB Picks & Predictions
Game Start: 4/23/2025, 1:40 AM UTC
Latest Odds: ARI -160 ; O/U 9

Rays vs Diamondbacks Prediction

The Tampa Bay Rays will be visiting Chase Field on Tuesday, where they will take on the Arizona Diamondbacks. Get the rest of our free MLB picks here! The Rays come into this series with an 9-13 record which places them fifth in the AL East. Tampa Bay has now lost 5 of their last 6 games, as they are coming off a 4-0 loss against the New York Yankees on Sunday. Zack Littell will be Tampa Bay’s starting pitcher on Tuesday, he’s sitting with a 5.48 ERA to go along with his 0-4 record. The Rays are scoring 4.5 runs per game, while batting .265 at the plate.

The Arizona Diamondbacks currently sit fourth in the NL West, as they enter this game with a 13-9 record. The Diamondbacks have won 7 of their last 10 heading into this one, most recently defeating the Cubs 3-2 on Sunday. Brandon Pfaat will be the starting pitcher for the Diamondbacks in this game, he’s posted a 3.04 ERA to go along with his 3-1 record. Arizona ranks third in the MLB with 5.6 runs per game. The Diamondbacks have allowed 8.1 hits and 4.8 runs per game.

Rays vs Diamondbacks Pick Analysis

Tampa Bay comes into this game on a major slump, while Arizona continues to play their best baseball of the season. Expect the momentum from the Diamondbacks to continue on Tuesday, leading them to cover -1.5 spread. Final score prediction, Diamondbacks win 5-3.

Our Free MLB Pick for Arizona Diamondbacks vs Tampa Bay Rays

Arizona Diamondbacks -1.5