Cardinals vs Pirates Picks and Prediction – 7/2/2025

NL Central Division foes will wrap up their series on Wednesday afternoon, when the St. Louis Cardinals take on the Pittsburgh Pirates from PNC Park. Be ready for the baseball season with all of our MLB predictions. The Cardinals (47-40) are two games below .500 on the road and are 3.5 games out of first place. Last night, St. Louis batters went 1-for-13 with runners in scoring position and left ten men on base during a 1-0 road loss. 

Thirty-five year old righty Sonny Gray (8-2 3.36 ERA) is quietly putting together another solid season for the Cardinals. Through 93 plus innings, Gray has struck out 101 batters and owns a solid 1.09 WHIP.

The Pittsburgh Pirates have reeled off five straight victories and are trying to climb out of the division cellar. During Tuesday’s home victory, Pittsburgh finally broke through in the eighth inning on a Henry Davis sacrifice fly that scored Ke’Bryan Hayes. SP Paul Skenes scattered five hits across five shutout frames and did not factor in the decision for the Pirates (37-50), who improved to 25-21 at home. 

The Pirates will counter with twenty-nine year old righty Mitch Keller (2-10 3.90 ERA) in the series finale. Last time out, Keller (5.1 IP) allowed five hits and one run during a 9-1 home victory versus New York.

St. Louis OF Jordan Walker (appendix) is expected to be activated from the 10-day injured list on Friday. Through 87 games, St. Louis ranks 15th in OPS and 8th in runs scored. For the season, Pittsburgh ranks 28th in OPS and 26th in runs scored. Take the Pirates to win at home. Final Score Prediction, Pittsburgh Pirates win 4-3.