Cardinals vs Phillies Picks and Prediction – 5/12/2025

Citizens Bank Park will play host to a Monday night MLB clash between the St. Louis Cardinals and the Philadelphia Phillies. Be ready for the baseball season with all of our MLB predictions. The Cardinals (22-19) are riding an eight-game winning streak and are just a game behind Chicago for the top spot in the NL Central Division. On Sunday, Lars Nootbar led off the game with a home run and Nolan Arenando added a two-run shot to power St. Louis to a 6-1 road triumph against Washington.

Twenty-five year old southpaw Matthew Liberatore (3-3 3.07 ERA) will head to the hill for the Cardinals in this contest. In his last start, Liberatore (7 IP) allowed one run and struck out eight batters during a 22-1 home victory versus Pittsburgh. 

The Philadelphia Phillies have won 13 of their first 19 home games and trail New York by 1.5 games for first place in the NL East Division. Last night, Philadelphia SP Zach Wheeler (4-1) was dominant with eight strikeouts and lasted seven innings during a 3-0 road victory against Cleveland. DH Kyle Schwarbwer homered twice and drove in three runs to provide the offense for the Phillies (24-16).

Philadelphia manager Rob Thomson will give the nod to talented left-hander Cristopher Sanchez (4-1 2.89 ERA) on Monday. Through 37 plus innings, Sanchez has struck out 44 batters and owns a 1.23 WHIP.

Philadelphia RP Jose Ruiz is on the 15-day injured list with neck spasms and is eligible to return this week. Through 41 games, St. Louis ranks 12th in OPS and 11th in runs scored. For the season, Philadelphia ranks 11th in OPS and 10th in runs scored. Take the Cardinals to win on the road. Final Score Prediction, St. Louis Cardinals win 5-3.