Cardinals vs Mets Picks and Prediction – 4/20/2025

By: David Anicetti |

Last Updated: 04/19/2025 at 7:15 PM ET

St. Louis Cardinals at New York Mets 04/20/25 - MLB Picks & Predictions
Game Start: 4/20/2025, 5:40 PM UTC
Latest Odds: NYM -137 ; O/U 7.5

Cardinals vs Mets Prediction

The St Louis Cardinals will conclude a four-game series on the road Sunday versus the New York Mets. St Louis dropped to 9-11 following its 5-4 loss to New York on Friday in the second game of the series. The Cardinals also lost the first game of the series 4-1 on Thursday. The Cardinals have lost three of the last four and trail first-place in the National League Central by three games. Keep up to date with all the MLB action with our expert MLB picks.

Brendan Donovan is batting .380 with 13 RBI, 30 hits, and an on-base percentage of .412 to lead St Louis in the four categories. Ivan Herrera is the leader in home runs with four. The Cardinals are batting .270 with a .416 slugging percentage. On Sunday, St Louis will send Sonny Gray to the mound. The right-hander is 3-0 with a 3.13 ERA, 23 Ks, and 3 BBs.

The New York Mets improved to 13-7 following their walk-off win on Friday night. Francisco Lindor led off the bottom of the ninth with a home run to give the Mets the win. The Mets had earlier blown a late lead before Lindor’s heroics. New York is first in the National League East, one game ahead of the Philadelphia Phillies, and has won four of the last six. 

Pete Alonso is batting .348 with five home runs, 21 RBI, 24 hits, and an on-base percentage of .465 to lead New York in the five statistical categories. Brandon Nimmo is second in home runs with four and second in RBI with nine. On Sunday, the New York Mets will send Clay Holmes to the mound. The right-hander is 2-1 with a 3.66 ERA, 28 Ks, and 11 BBs. 

Cardinals vs Mets Pick Analysis

St Louis will pick up a victory on the road Sunday versus the New York Mets, but the play here is UNDER. The UNDER has cashed in seven of the Cardinals' last nine and 10 of the Mets' last 14. St Louis starter Sonny Gray has had two consecutive strong outings, allowing one run on six hits across 12 innings. New York starter Clay Holmes at a strong outing last Monday, allowing one run on two hits across five innings. Final Score Prediction: St Louis Cardinals win but our best play is UNDER 4-2.

Our Free MLB Pick for New York Mets vs St. Louis Cardinals

Under 7.5