Cardinals vs Mets Picks and Prediction – 4/19/2025

The St Louis Cardinals play the third game of a four-game series on the road Saturday versus the New York Mets. St Louis is 9-10 following a 4-1 loss to the Mets on Thursday in the opening game of the series. The Cards have lost two of the last three. St. Louis trails first place in the National League Central by two games. Keep up to date with all the MLB action with our expert MLB picks.

Brendan Donovan is batting .373 with 12 RBI and 28 hits to lead St Louis in the three categories. Ivan Herrera is the leader in home runs with four, and Lars Nootbaar is the leader in on-base percentage at .422. The Cardinals are batting .272 with a .442 slugging percentage. On Saturday, St Louis will send Matthew Liberatore to the mound. The left-hander is 1-1 with a 3.93 ERA, 18 Ks, and 1 BBs.

The New York Mets improved to 11-8 following Thursday’s 4-1 victory over the Cardinals. Mark Vientos hit his first home run of the season in the second inning, leading to four runs by the Mets. New York is first in the National League East, one game ahead of the Philadelphia Phillies, but is just 3-3 over its last six. However, the Mets are 10-4 over the last 14. 

Pete Alonso is batting .343 with five home runs, 21 RBI, 23 hits, and an on-base percentage of .451 to lead New York in the five statistical categories. Brandon Nimmo is second in home runs with four and second in RBI with nine. On Saturday, the New York Mets will send Kodai Senga to the mound. The right-hander is 2-1 with a 1.06 ERA, 16 Ks, and 5 BBs. 

New York has won each of its last five head-to-head versus St Louis. The Cardinals have lost six of the last seven played on the road. St Louis starter Matthew Liberatore is coming off a strong outing in which the left-hander allowed no runs on three hits across six innings. New York starter Kodai Senga has had three consecutive solid outings, allowing two runs across 17 innings. Final Score Prediction: New York Mets win 6-2.