Cardinals vs Brewers Picks and Prediction – 6/15/2025

On Sunday, the St. Louis Cardinals (36-34) face off against the Milwaukee Brewers (38-33) at American Family Field in Milwaukee, Wisconsin. Keep up to date with all the MLB action, with our expert MLB picks.

Milwaukee comes into this matchup on a two-game winning streak and has won three of their last five games prior to their game against St. Louis on Saturday. In their narrow 3-2 victory over the St. Louis Cardinals on Friday, Brewers pitcher Freddy Peralta delivered a strong performance on the mound. He lasted six innings, giving up only four hits and a single earned run while walking one batter and striking out six. Offensively, Christian Yelich has been Milwaukee’s main power hitter this season, leading the team with thirteen home runs. Not far behind, Jackson Chourio has contributed twelve homers, making him the Brewers’ second-leading home run hitter. Yelich has also been Milwaukee’s biggest run producer so far, collecting a team-high forty-two RBIs. When it comes to consistency at the plate, Sal Frelick stands out as the team’s top hitter, carrying a .296 batting average. Recently, however, the Brewers’ offense has cooled slightly; in their past five games, they have averaged just 3.2 runs per contest. This stretch has left them six games behind the Chicago Cubs in the race for first place in the NL Central division. As they prepare to face the Cardinals again, Milwaukee hopes to close the gap in the standings with another win. Throughout the season, the Brewers have averaged 4.3 runs per game, reflecting an overall solid offensive output despite their recent dip in scoring.

St. Louis enters this game on a six-game losing streak prior to their game against Milwaukee on Saturday. In their close 3-2 defeat to Milwaukee on Friday, Cardinals starter Erick Fedde took the mound for 5 and 1/3 innings, during which he gave up four hits, allowed three earned runs, walked one batter, and struck out five. Offensively, Willson Contreras has been St. Louis’ primary power hitter this season, leading the team with nine home runs. Following closely behind, both Nolan Arenado and Lars Nootbaar have contributed eight home runs each, tying them for second-most on the squad. Contreras has also driven in the most runs, topping the team with 44 RBIs this season. Brendan Donovan has been the Cardinals’ most consistent hitter for average, currently batting .310. Defensively, St. Louis has struggled of late, surrendering an average of 5.8 runs per contest over their last five games. This recent slide has left the Cardinals trailing the Brewers by just one and a half games for second place in the NL Central. Looking ahead, the Cardinals are aiming to get their offense firing on all cylinders and build momentum as they chase the division lead. So far this season, they are averaging 4.5 runs scored per game.

The Brewers and the Cardinals have played some closely matched games against each other this year, keeping the competition lively whenever they meet. St. Louis will send Miles Mikolas to the mound; he's posted a 4-3 win-loss record so far in the season with an ERA of 4.48, indicating he’s had some ups and downs but generally holds his own. On the other side, Milwaukee’s starting pitcher will be Quinn Priester, who has been slightly more effective this season, boasting a 4-2 record and a 3.65 ERA. Priester’s numbers suggest he’s been able to limit opponents’ scoring a bit better than Mikolas, which could give the Brewers a slight edge in the pitching matchup. Final Score Prediction, Milwaukee Brewers win 9-5.