Cardinals vs Reds Picks and Prediction – 4/30/2025

The St. Louis Cardinals play the third game of a four-game series on the road Wednesday versus the Cincinnati Reds. St Louis is 12-17 following its 3-1 loss to Cincinnati on Monday in the opening game of the series. St Louis has lost two straight and eight of the last 11. The Cardinals are fourth in the National League Central, five games behind the first-place Chicago Cubs. Keep up to date with all the MLB action with our expert MLB picks.

Brendan Donovan is batting .349 to lead St Louis and has a team high of 37 hits. Ivan Herrera is the leader in home runs with four, while Lars Nootbaar is the leader in hits with 17 and on-base percentage at .405. St Louis is batting .263 with a .397 slugging percentage. On Wednesday, St Louis will send Steven Matz to the mound. The left-hander is 1-2 with a 1.80 ERA, 14 Ks, and 3 BBs.

The Cincinnati Reds improved to 16-13 following Monday’s two-run win over the St Louis Cardinals. Nick Martinez threw six strong innings for the Reds. Cincinnati's Gavin Lux, Noelvi Marte, and Jose Trevino each had one RBI. Cincinnati has won five straight, and the Reds have moved within one game of the first-place Chicago Cubs in the National League Central.

Gavin Lux is batting .352 with an on-base percentage of .438 to lead Cincinnati in both categories. Austin Hays is the leader in home runs with five. Elly De La Cruz is the leader in RBI with 24, and TJ Friedl is the leader in hits with 32. On Wednesday, the Cincinnati Reds will send Andrew Abbott to the mound. The left-hander is 2-0 with a 3.60 ERA, 20 Ks, and 8 BBs.

The Cincinnati Reds are on fire, having won each of the last five games through their victory on Monday over St Louis. Although Cincinnati starter Andrew Abbott is coming off a poor performance, expect to win at home on Wednesday. The Reds are 5-2 in the last seven played at home. St Louis starter Steven Matz has made five appearances but just one start this season. Final Score Prediction: Cincinnati Reds win 6-2.