Cardinals vs Braves Picks and Prediction – 4/21/2025

The St. Louis Cardinals open a three-game series on the road Monday versus the Atlanta Braves. St. Louis is 9-12 following its 3-0 loss to the New York Mets on Saturday and will complete a four-game series with the Mets on Sunday. St Louis has lost three straight and four of the last five. The Cardinals are fourth in the National League Central, four games behind the first-place Chicago Cubs. Keep up to date with all the MLB action with our MLB picks.

Brendan Donovan is batting .361 with 13 RBI and 30 hits, to lead St Louis in each of the three categories. Ivan Herrera is the leader in home runs with four. Nolan Arenado has a team-best .395 on-base percentage. St Louis is batting .264 with a .406 slugging percentage. On Monday, St Louis will send Erick Fedde to the mound. The right-hander is 1-2 with a 3.43 ERA, 10 Ks, and 11 BBs.

The Atlanta Braves improved to 7-13 following Saturday’s 4-3 victory over the Minnesota Twins. Atlanta has won each of the first two games of its three-game series with Minnesota that concludes on Sunday. Alex Verdugo collected four hits, including a single to knock in the go-ahead run for the Braves. Atlanta is last in the National League East, 6 ½ games behind the first-place New York Mets.

Marcell Ozuna is batting .304 with an on-base percentage of .466 to lead Atlanta in both categories. Austin Riley is the leader in home runs with five, RBI with 12, and hits with 22. Atlanta is batting .229 with a .379 slugging percentage. On Monday, the Atlanta Braves will send Spencer Schwellenbach to the mound. The right-hander is 1-1 with a 2.55 ERA, 22 Ks, and 5 BBs.

The Atlanta Braves are last in the National League East and have lost 13 of the last 20. Atlanta’s starting pitcher struggled last time out and will face a St. Louis starter who has had two straight solid outings. St Louis starter Erick Fedde has had two consecutive strong outings, allowing one run across 12 Innings. Atlanta starter Spence Schwellenbach was roughed up last time out, allowing six runs on six hits across 4.2 innings. Final Score Prediction: St Louis Cardinals win 5-4.