Mariners vs Twins Picks and Prediction – 6/26/2025

By: Eddie Kline |

Last Updated: 06/25/2025 at 10:08 PM ET

Seattle Mariners at Minnesota Twins 06/26/25 - MLB Picks & Predictions
Game Start: 6/26/2025, 5:10 PM UTC
Latest Odds: MIN -120 ; O/U 9

Mariners vs Twins Prediction

MLB Network will feature a Thursday afternoon clash between the Seattle Mariners and the Minnesota Twins from Target Field. Be ready for the baseball season with all of our MLB predictions. The Mariners (41-38) have won seven of their last 11 games and trail AL West Division leading Houston by five games. Last night, Seattle batters managed just three hits and were retired by strikes 11 times during a 2-0 road loss against Minnesota. 

Twenty-six year old righty Emerson Hancock (3-3 5.43 ERA) will head to the hill for the Mariners in this contest. Last time out, Hancock was rocked for nine runs in four innings during a 10-7 road loss against the Chicago Cubs. 

The Minnesota Twins are two games above .500 at home and are sitting in fourth place in the AL Central Division standings. On Wednesday, Minnesota was able to snap a five-game losing streak with a Willi Castro RBI single and a Kody Clemens solo shot. SP Joe Ryan (8-3) fired six shutout frames and fanned eight batters to earn the win for the Twins, who improved to 38-42 overall. 

Minnesota manager Rocco Baldelli will turn to righty Simeon Woods Richardson (2-4 5.06 ERA) in the series finale. The Twins have dropped Woods Richardson’s last three starts and he has surrendered nine runs across his last 15 plus frames.

Mariners vs Twins Pick Analysis

Minnesota 3B Royce Lewis (hamstring) has started change of direction running and hopes to return to the lineup early next month. Through 79 games, Seattle ranks 8th in OPS and 12th in runs scored. For the season, Minnesota ranks 16th in OPS and 17th in runs scored. Take the Twins to win at home. Final Score Prediction, Minnesota Twins win 5-4.

Our Free MLB Pick for Minnesota Twins vs Seattle Mariners

Minnesota Twins -120