Mariners vs Reds Picks and Prediction – 4/17/2025

The Great American Ball Park will be the scene for a Thursday afternoon MLB interleague battle between the Seattle Mariners and the Cincinnati Reds. Be ready for the baseball season with all of our MLB predictions. The Mariners have started the season with an 8-5 home record and will need more offensive production to challenge for the AL West Division crown. Despite owning a .203 batting average, C Cal Raleigh leads the Mariners with five long balls.

Twenty-five year old righty Bryan Woo (2-0 2.84 ERA) continues to be overlooked in the Pacific Northwest. Last time out, Woo (7 IP) allowed one run and struck out seven batters during a 9-2 home victory versus Texas. 

The Cincinnati Reds rank third in baseball with a 2.94 ERA and are the only team with a sup 1.00 WHIP. Flame-throwing righty Hunter Greene is putting it all together and has the potential to win a Cy Young Award. Cincinnati SS Elly De La Cruz is struggling at the plate with a .224 average, but has driven in a team-high 18 runs. 

Cincinnati manager Terry Francona will turn to twenty-eight year old righty Brady Singer (3-0 3.18 ERA) on Thursday. Through 17 innings, Singer has fanned 18 batters and owns a solid 1.06 WHIP.

Seattle SP George Kirby (shoulder) threw a bullpen session over the weekend and hopes to rejoin the rotation early next month. Through 18 games, Seattle ranks 27th in OPS and 21st in runs scored. For the regular season, Cincinnati ranks 28th in OPS and 16th in runs scored. Take the under. Final Score Prediction, Seattle Mariners win 4-1.