Mariners vs Red Sox Picks and Prediction – 4/23/2025

The Seattle Mariners will play the second game of a three-game series on the road Wednesday at Fenway Park versus the Boston Red Sox. Seattle is 12-10 following an 8-3 victory over the Toronto Blue Jays on Sunday. Cal Raleigh and Rowdy Tellez hit two-run home runs for the Mariners. Seattle is second in the American League West, one game behind the first-place Texas Rangers. Keep up to date with all the MLB action with our expert MLB picks.

Jorge Polanco is batting .346 to lead Seattle. Cal Raleigh is the leader in home runs with 9 and hits with 20. Randy Arozarena is the leader in RBI with 17, and J.P. Crawford leads in on-base percentage with .377. Seattle is batting .222 with a .393 slugging percentage. On Wednesday, the Seattle Mariners will send Emerson Hancock to the mound. The right-hander is 0-1 with a 12.71 ERA, 4 Ks, and 1 BBs.

The Boston Red Sox improved to 13-11 following Monday’s 4-2 victory over the Chicago White Sox. The Red Sox have won five of the last six. Walker Buehler threw 7 strong innings for Boston on Monday, and Kristian Campbell had a two-run single to put the Red Sox ahead for good. The Red Sox are second in the American League East, 1 ½ games behind the first-place New York Yankees.

Trevor Story is batting .337 with five home runs and 30 hits to lead Boston in the three categories. Alex Bregman is the leader in RBI with 16, and Kristian Campbell is the leader in on-base percentage with .418. Boston is batting .246 with a .394 slugging percentage. On Tuesday, Boston will send Sean Newcomb to the mound. The left-hander is 0-2 with a 3.63 ERA, 19 Ks, and 9 BBs.

Seattle has lost 13 of the last 20 head-to-head versus Boston. Boston has won five of its last six overall, and the Red Sox are 4-1 in the last five played at home. In two outings this season, Seattle starter Emerson Hancock has given up eight runs across 5.2 innings. Boston starter Sean Newcomb is coming off a strong outing in which the right-hander allowed no runs on four hits across 4.2 innings. Final Score Prediction: Boston Red Sox win 5-2.