Giants vs Nationals Picks and Prediction – 5/24/2025

Nationals Park will play host to a Saturday afternoon MLB clash between the San Francisco Giants and the Washington Nationals. Be ready for the baseball season with all of our MLB predictions. The Giants (30-21) are a game above .500 on the road and are 1.5 games behind NL West Division leading Los Angeles. Last night, SP Landen Roupp (3-3) fired six shutout frames to lead San Francisco to a 4-0 road victory against Washington. 

San Francisco manager Bob Melvin has yet to announce a starting pitcher for this matchup. The Giants currently rank fifth in the majors with a 3.34 ERA and have logged 15 quality starts. 

The Washington Nationals have won six of their last ten games and are 9.5 games off the pace in the NL East Division race. On Friday, Washington SP MacKenzie Gore (2-5) struck out nine batters in six innings and was the hard luck loser. 2B Luis Garcia Jr. had two of the five hits for the Nationals (23-28) , who fell to 12-13 at home. 

Washington skipper Dave Martinez will counter with right-hander Jake Irvin (3-1 3.88 ERA) on Saturday. Last time out, Irvin (6.1 IP) allowed two runs and struck out six batters during a 10-6 road victory against Baltimore. 

Washington OF Dylan Crews has been placed on the 10-day injured list with a lower back injury. Through 51 games, San Francisco ranks 19th in OPS and 9th in runs scored. For the season, Washington ranks 17th in OPS and 12th in runs scored. Take the Nationals to win at home. Final Score Prediction, Washington Nationals win 5-3.