Giants vs Padres Picks and Prediction – 4/30/2025

The San Francisco Giants conclude a short two-game series on the road Wednesday versus the San Diego Padres. San Francisco is 19-10 and tied for first in the National League West with the Los Angeles Dodgers. San Francisco defeated the Texas Rangers 3-2. San Francisco defeated Texas in two of three over the weekend. The Giants have won two straight and four of the last five. Keep up to date with all the MLB action with our expert MLB picks.

Jung Hoo Lee leads San Francisco in batting, averaging .324, and is the leader in hits with 35. Wilmer Flores is the leader in home runs with seven and in RBI with 28. Mike Yastrzemski is the leader in on-base percentage at .394. San Francisco is batting .229 with a .377 slugging percentage. On Wednesday, the Giants will send Landen Roupp to the mound. The right-hander is 2-1 with a 4.56 ERA, 31 Ks, and 11 BBs.

The San Diego Padres dropped to 17-11 following Sunday’s 4-2 loss to the Tampa Bay Rays. San Diego was swept in its three-game series by Tampa Bay. The Padres have lost four straight and seven of the last nine. San Diego has dropped to third in the National League West, 1 ½ games behind co-leaders the San Francisco Giants and Los Angeles Dodgers.

Fernando Tatis Jr is batting .346 with eight home runs, 18 RBI, 36 hits, and an on-base percentage of .415, to lead San Diego in the categories. Jackson Merrill is one of four players for San Diego with three home runs apiece. The Padres are batting .255 with a .386 slugging percentage. On Wednesday, San Diego will send Michael King to the mound. The right-hander is 3-1 with a 2.18 ERA, 40 Ks, and 11 BBs.

San Diego will win on Wednesday when hosting San Francisco, but the play here is UNDER. The UNDER has cashed in four of San Francisco's last five and each of San Diego's last five. San Francisco starter Landen Roupp has allowed nine runs on 17 hits across the last 15.2 innings. San Diego starter Michael King has had three consecutive strong outings, allowing two runs on 10 hits across 19.2 innings. Final Score Prediction: San Diego Padres win but our best play is UNDER 4-2.