Giants vs Phillies Picks and Prediction – 4/16/2025

The Philadelphia Phillies remain at home on Wednesday with the San Francisco Giants in town. The Phillies are averaging 4 runs scored per game with 7.9 hits. Philadelphia allowed 10 runs in their loss to the Giants on Monday. The Phillies are 2nd in the NL East. Stay up to date with our expert's MLB Picks. 

Aaron Nola will make his 4th start on the mound for the Philadelphia Phillies. Nola is 0-3 on the season with 16.1 innings pitched. Nola has 17 strikeouts and carries a 5.51 ERA. Nola pitched 5 innings in his last start allowing 2 runs on 5 hits. 

The San Francisco Giants entered this week with 12 wins. The Giants have won seven of their last ten games. San Francisco is averaging 5.3 runs scored per game with 7.6 hits. The Giants are 8-2 on the road this season. 

Robbie Ray will make his 4th start on the hill for the San Francisco Giants. Ray is 3-0 with 15.1 innings pitched. Ray has 13 strikeouts, 10 walks, and carries a 2.94 ERA. Ray pitched 4 innings in his last start allowing 1 run and 2 hits. 

Both Aaron Nola and Robbie Ray are hungry to get into the win column. Nola has pitched well over his last two starts but has had no run support. While Ray didn't make it past 4 innings in his last start. Watch for a pitching duel between these two veteran arms. Final Score Prediction, Philadelphia Phillies win, but the play is on the under 3-2.