Giants vs Twins Picks and Prediction – 5/11/2025

The San Francisco Giants conclude a three-game series on the road Sunday versus the Minnesota Twins. San Francisco is 24-15 following its 3-1 loss to Minnesota in the opening game of the series on Friday. Nevertheless, the Giants have won five of the last seven. San Francisco is 3rd in the National League West, two games behind the first-place Los Angeles Dodgers. Keep up to date with all the MLB action with our expert MLB picks.

Jung Hoo Lee is batting .293 to lead San Francisco and has a team-high 43 hits. Matt Chapman is the leader in home runs with eight, and Wilmer Flores is the leader in RBI with 33. Mike Yastrzemski is the leader in on-base percentage at .377. On Sunday, San Francisco will send Landen Roupp to the mound. The right-hander is 2-3 with a 4.89 ERA, 39 Ks, and 14 BBs.

The Minnesota Twins improved to 19-20 following Friday’s two-run victory over the San Francisco Giants. Chris Paddack was perfect on the mound into the sixth inning for Minnesota. The win was Minnesota's sixth straight, since snapping a four-game losing streak. The Twins are fourth in the American League Central, seven games behind the first-place Detroit Tigers.

Byron Buxton is batting .279 with nine home runs, 25 RBI, and 39 hits to lead Minnesota in the four categories. Ty France is the leader in on-base percentage at .344. Minnesota is batting .237 with a .371 slugging percentage. On Sunday, the Minnesota Twins will send Pablo Lopez to the mound. The right-hander is 3-2 with a 2.18 ERA, 37 Ks, and 5 BBs.

Minnesota has won each of its last six overall, and the Twins have won each of the last seven played at home on Target Field. San Francisco starter Landen Roupp has been hit hard in five straight outings, allowing 15 runs on 29 hits across 25 innings. Minnesota starter Pablo Lopez has pitched very well in each of the last five outings, allowing six runs on 18 hits across 28 innings. Final Score Prediction: Minnesota Twins win 6-2.