Giants vs Dodgers Picks and Prediction – 6/15/2025

National League West rivals meet again at Dodger Stadium on Saturday at 5:00 PM ET when the 41-29 San Francisco Giants take on the 41-29 Los Angeles Dodgers. San Francisco took the series opener with a 6-2 win Friday night. It’ll be Kyle Harrison (1-1, 4.56 ERA) starting for the Giants, going up against Dustin May (3-4, 4.46 ERA) for the Dodgers in this final game of the series. Elevate your MLB game with our top-notch MLB picks.

San Francisco has won four of its last five games, including last night’s win, where the bats delivered and the bullpen held the Dodgers to just two runs. This team has started to click on the road, improving to 19-18 away from home. The Giants are playing scrappy ball lately and continue to win tight contests, with three of those recent wins decided by two runs or less.

On the mound, the Giants come in with a solid 3.12 ERA and 1.21 WHIP, holding opponents to a .230 average. The pitching staff has racked up 604 strikeouts and walked just 218. Kyle Harrison, a young lefty, will need to be sharper than his 4.56 ERA and 1.27 WHIP suggest. Wilmer Flores leads the club with 51 RBIs and 11 homers, while Matt Chapman has added 12 dingers. Heliot Ramos has been a consistent bat with a .294 average and .366 OBP. 

Los Angeles has lost two of the last three following Friday’s 6-2 loss. The Dodgers struggled to get key hits despite having a potent lineup and playing at home where they're 23-12. Before that, they took two of three from the Padres and are still one of the league's most dangerous teams at the plate.

The Dodgers own a .263 team average with 106 home runs and a .339 OBP. The pitching has been inconsistent with a 4.19 ERA and 1.32 WHIP. Dustin May has a 4.46 ERA over 66.2 innings with 64 strikeouts and 26 walks. Offensively, Shohei Ohtani is a threat with 23 homers and 39 RBIs, while Freddie Freeman leads the team in average at .341. Teoscar Hernández has also chipped in with 48 RBIs. The bullpen is a bit banged up with Blake Treinen and Giovanny Gallegos among the pitchers on the shelf.

The Giants have been more consistent lately and got a boost by winning the series opener in convincing fashion. Kyle Harrison isn’t dominant, but the bullpen and defense behind him have been better than the Dodgers’, who are allowing a full run more per game. San Francisco’s 3.12 ERA and lower WHIP give them a defensive edge, and with Flores and Ramos producing, the bats can back it up. Final Score Prediction: San Francisco Giants win 5-4.