Giants vs White Sox Picks and Prediction – 6/29/2025

On Sunday, the San Francisco Giants (45-37) face off against the Chicago White Sox (26-56) at Rate Field in Chicago, Illinois. Keep up to date with all the MLB action, with our expert MLB picks.

Chicago comes into this matchup on a one-game losing streak and has dropped three of their last five games prior to their second game of the series against San Francisco. During Friday’s 3-1 defeat against San Francisco, Chase Meidroth managed one hit in four at-bats and was responsible for scoring the White Sox’s lone run of the game. This season, Miguel Vargas has emerged as Chicago’s top power hitter, leading the team with 10 home runs. Close behind him is Andrew Benintendi, who has contributed nine home runs to the team’s total. Vargas isn’t just providing power; he’s also been the most productive run producer for the White Sox, accumulating 34 RBIs so far this year. In addition, Vargas holds the highest batting average on the team, hitting .234 for the season. Despite a few individual bright spots, the team has struggled overall, especially on the pitching side, allowing an average of 4.4 runs per game over their last five outings. As a result, the White Sox are going through yet another rebuilding season. Offensively, Chicago has also faced challenges, averaging just 3.4 runs per game—a statistic that highlights their need for more consistent production at the plate.

San Francisco enters this game on a one-game winning streak, but has dropped three of their last five games prior to their second game of the series against Chicago. In Friday’s 3-1 victory over the White Sox, the Giants were helped by Patrick Bailey, who went 1-for-3 at the plate, driving in two runs and scoring once himself. This season, Heliot Ramos has been San Francisco’s top power hitter, leading the team with 13 home runs. Close behind him is Matt Chapman, who has contributed 12 home runs so far, making him the Giants’ second-best in that category. When it comes to producing runs, Wilmer Flores stands out as the team leader, having racked up 55 RBIs to this point in the year. Ramos is also setting the pace for the Giants in hitting, boasting a team-high batting average of .282. Defensively, San Francisco has struggled lately, surrendering an average of 6 runs per game over their last five contests. Despite this, they currently hold a slim half-game lead over both San Diego and St. Louis in the race for the NL's final wild card playoff spot. With the regular season winding down, the Giants are looking to snap out of their recent slump and solidify their position in the postseason hunt. Overall this year, San Francisco’s offense has averaged 4.2 runs scored per game.

San Francisco's offense has been stagnant lately, and they're aiming to exploit the White Sox's struggling pitching staff as they try to prevent their season from taking a turn for the worse. On the mound for San Francisco is veteran starter Justin Verlander, who has yet to earn a win this season, posting a record of 0-5 along with a 4.52 ERA. Final Score Prediction, San Francisco Giants win 5-4.