San Francisco Giants at Chicago Cubs 9/11/22 - MLB Picks & Predictions

Last Updated: 09/11/2022 at 9:42 AM ET

San Francisco Giants at Chicago Cubs 9/11/22 - MLB Picks & Predictions

The San Francisco Giants close out a three-game series on the road at Wrigley Field Sunday against the Chicago Cubs. San Francisco is 65-73 following its 4-2 loss to Chicago in the opening game of the series on Friday. The Giants have lost five straight and San Francisco is fourth in the National League West, 29 ½ games behind first place and out of playoff contention. Find out who else is playing great with our free MLB previews.

Second baseman Thairo Estrada is batting .257 to lead San Francisco and has a team high 108 hits. Left fielder Joc Pederson is the leader in home runs with 22 while second baseman Wilmer Flores is the leader in RBIs with 63 and on-base percentage at .320. San Francisco has not announced its starting pitcher for Sunday's final game of a three-game series against Chicago.

Chicago improved to 58-80 following its two-run win over San Francisco on Friday. Drew Smyly gave up just one hit over seven shutout innings and Nico Hoerner and Yan Gomes each homered in the victory. However, Chicago has lost nine of the last 12. The Cubs are third in the National League central, 22 ½ games behind first-place and out of playoff contention.

Shortstop Nico Hoerner is batting .288 to lead Chicago, while third base Patrick Wisdom is the leader in home runs with 22. Left fielder Ian Happ is the leader in RBIs with 64 and hits with 133, while catcher Willson Contreras is the leader in on-base percentage at .351. On Sunday, the Chicago Cubs will send Wade Miley to the mound. The left-hander is 1-0 with a 3.13 ERA, 18 Ks and 10 BBs.

Chicago has dominated San Francisco at home, winning 18 of the last 24 versus the Giants at Wrigley Field. San Francisco is struggling as the Giants have lost each of the last five overall and San Francisco has lost 20 of the last 26 played on the road. Chicago starting pitcher Wade Miley has had four consecutive solid outings allowing five runs on 12 hits across 20 innings resulting in Chicago winning three of the four. Final Score Prediction, Chicago Cubs win 5-2.

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