Giants vs Braves Picks and Prediction – 7/22/2025

By: David Anicetti |

Last Updated: 07/21/2025 at 9:13 PM ET

San Francisco Giants at Atlanta Braves 07/22/25 - MLB Picks & Predictions
Game Start: 7/22/2025, 11:15 PM UTC
Latest Odds: ATL -110 ; O/U 9.5

Giants vs Braves Prediction

The San Francisco Giants will play the second game of a three-game series on the road Tuesday versus the Atlanta Braves. San Francisco is 52-48 and lost to the Toronto Blue Jays 8-6 on Sunday. The Giants have lost five straight and six of the last seven. San Francisco is third in the National League West, six games behind the first-place Los Angeles Dodgers. Keep up to date with all the MLB action with our MLB previews.

Heliot Ramos is batting .267 with 101 hits to lead San Francisco in both categories. Willy Adames leads the Giants in home runs with 14, while Wilmer Flores leads in RBI with 55, and Mike Yastrzemski is the leader in on-base percentage with .343. On Tuesday, San Francisco will send Landen Roupp to the mound. The right-hander is 6-6 with a 3.27 ERA, 89 Ks, and 41 BBs.

The Atlanta Braves are 43-55 following Sunday’s 4-2 loss to the New York Yankees. Atlanta opened the series versus New York with a victory, but lost each of the last two versus the Yankees and has lost three of its last four overall. Atlanta is fourth in the National League East, trailing the first-place Philadelphia Phillies by 12 ½ games.

Austin Riley is batting .274 with 104 hits to lead Atlanta in both categories. Matt Olson leads the Braves in home runs with 17 and RBI was 64, while Marcell Ozuna is the team leader in on-base percentage with .363. Atlanta is batting .244 with a .391 slugging percentage. On Tuesday, Atlanta will send Davis Daniel to the mound. The right-hander is 0-0 with a 1.80 ERA, 6 Ks, and 3 BBs.

Giants vs Braves Pick Analysis

San Francisco will win on the road Tuesday when visiting Atlanta, but the play here is UNDER. The UNDER has cashed in four of the Giants’ last six on the road versus Atlanta and in seven of Atlanta’s last nine overall versus the Giants. San Francisco starter Landen Roupp has made five straight strong outings, allowing four runs on six hits across 26.1 innings. Atlanta starter Davis Daniel is coming off a strong outing in which the right-hander gave up one run on two hits across four innings. Final Score Prediction: San Francisco Giants win but our best play is UNDER 4-2.

Our Free MLB Pick for Atlanta Braves vs San Francisco Giants

Under 9.5