Padres vs Giants Picks and Prediction – 6/5/2025

The San Diego Padres remain on a short road trip Thursday with another game in San Francisco against the Giants. San Diego comes into this matchup with 35 wins and 24 losses on a three-game winning streak after consecutive extra inning wins in this series. Offensively San Diego has a .248 batting average as the Padres and scored 246 runs on 486 hits this season. San Diego Power has been there as well this season with 53 home runs and a .380 team slugging percentage. Stay up to date with our MLB Picks.

Manny Machado leads the San Diego offense this season with a .315 batting average and 69 hits on the season. Luis Arraez has a .283 batting average and Xander Bogaerts has a .241 batting average. Gavin Sheets has a .260 batting average to go along with the team leading 34 RBI's. Fernando Tatis Jr. has a .265 batting average and leads San Diego with 13 home runs this season.

The San Francisco Giants stay home Thursday night five games above .500 after dropping three of the last four overall. Offensively San Francisco has a .231 batting average as the Giants score 250 runs on 465 hits. The San Francisco pitching has been solid as well this season with a 3.03 team ERA.

Heliot Ramos leads the San Francisco offense this season with a .293 batting average, eleven home runs, and 67 hits. Willy Adames has a .203 batting average and Jung Hoo Lee has a .269 batting average. Wilmer Flores has a .253 batting average to go along with the team leading 47 RBIs for San Francisco this season. Tyler Fitzgerald has a .263 batting average for the Giants this year but has played in just 40 total games.

The Giants have one of the better arms in the league on the mound Thursday and that will lead to the win. Look for the Giants pitching to stifle the Padres in this game leading to the home win. Take San Francisco Thursday night at home to get the win. Final Score Prediction, San Francisco Giants win 6-1.