Padres vs Giants Picks and Prediction – 6/4/2025

The San Francisco Giants will remain at home on Tuesday with the San Diego Padres in town. The Giants are 3rd in the NL West. San Francisco has won four of their last ten games and carry a 17-9 home field record. The Giants are averaging 4.2 runs scored per game. Stay up to date with our expert's MLB Picks. 

Landen Roupp will make his 12th start on the mound for the San Francisco Giants. Roupp is 3-4 on the season with 56 innings pitched. Roupp has 56 strikeouts and carries a 3.54 ERA. Roupp pitched 4 innings in his last outing allowing 1 earned run and 5 hits. 

The San Diego Padres are 2nd in the NL West. The Padres have won six of their last ten games. The Padres carry a losing road record into this series. San Diego is averaging 4.2 runs scored per game with 8.2 hits. 

The San Diego Padres beat the Giants 5-3 in their last meeting back in April. The Padres carry a .249 team batting average and have 53 home runs. San Diego carries a 3.61 team ERA. The Padres won their weekend series against the Pirates. 

The San Francisco Giants have been a very good home team this season. The Giants will feature Landen Roupp on the mound. Roupp has allowed just 1 earned run total through his last three starts. The Giants are a home favorite for good reason on Tuesday. Final Score Prediction, San Francisco Giants win 3-1.