Padres vs Giants Picks and Prediction – 6/3/2025

The San Diego Padres open a four-game series on the road Monday versus the San Francisco Giants. San Diego dropped to 32-24 following Saturday´s 5-0 loss to the Pittsburgh Pirates. However, San Diego has won four of the last six. The Padres are second in the National League West, three games behind the first-place Los Angeles Dodgers. Keep up to date with all the MLB action with our expert MLB picks.

Manny Machado is batting .308 with 64 hits and an on-base percentage of .375 to lead San Diego in the three categories. Fernando Tatis Jr is the leader in home runs with 13, and Gavin Sheets is the leader in RBI with 34.

San Diego is batting .249 with a .384 slugging percentage. On Monday, San Diego will send Stephen Kolek to the mound. The right-hander is 3-1 with a 4.11 ERA, 24 Ks, and 10 BBs.

The San Francisco Giants dropped to 32-26 following Saturday’s 1-0 loss to the Miami Marlins. San Francisco managed only eight hits and stranded 11 runners as the Giants were 0-for-6 with runners in scoring position. San Francisco starter Robbie Ray gave up just one run in seven innings but suffered the loss with no run support. San Francisco is third in the NL West, four games behind first-place Los Angeles.

Heliot Ramos is batting .292 with 63 hits to lead San Francisco in both categories. Wilmer Flores is the leader in home runs with 10 and in RBI with 46, while Matt Chapman is the leader in on-base percentage at .360. San Francisco is batting .233 with a .375 slugging percentage. On Monday, San Francisco will send Logan Webb to the mound. The right-hander is 5-5 with a 2.82 ERA, 84 Ks, and 17 BBs.

Although both starting pitchers have given up plenty of runs over the last two starts, the play here is UNDER. The UNDER has cashed in 10 of San Diego's last 15, and each of San Francisco's last eight. San Francisco is 16th in runs scored, and San Diego is only 19th. The Padres are 20th in slugging percentage, and the Giants are just 24th. Final Score Prediction: San Francisco Giants win but our best play is UNDER 4-2.