Padres vs Yankees Picks and Prediction – 5/5/2025

Two of the top teams in baseball will square off on Monday night, when the San Diego Padres travel to the Bronx to face the New York Yankees. Be ready for the baseball season with all of our MLB predictions. The Padres (22-11) are riding a five-game winning streak and are just a game out of first place in the NL West Division. On Sunday, SS Xander Bogaerts went 2-for-4 with three RBIs to lead San Diego to a 4-0 road victory against Pittsburgh. 

Thirty-two year old righty Nick Pivetta (5-1 1.78 ERA) will head to the hill for the Padres in this contest. San Diego has won Pivetta’s last four starts and he has allowed just four runs across his last 25 plus frames. 

The New York Yankees have split their previous ten games and hold a two-game lead over Boston for the top spot in the AL East Division. On Sunday, New York OF Cody Bellinger hit a two-run blast during a 7-5 home loss versus Tampa Bay. SP Will Warren (1-2) gave up five runs (3 ER) in four plus innings and took the loss for the Yankees (19-15), who fell to 11-7 at home. 

New York manager Aaron Boone will give the nod to talented southpaw Carlos Rodon (4-3 3.43 ERA) on Monday. Through 42 innings of work. Rodon has struck out 52 batters and owns a sparkling 0.98 WHIP.

New York 2B Jazz Chisholm Jr. has landed on the 10-day injured list with a right oblique issue and will miss the next 4-6 weeks. Through 33 games, San Diego ranks 13th in OPS and 18th in runs scored. For the season, New York ranks 1st in OPS and 2nd in runs scored. Take the Padres to win on the road. Final Score Prediction, San Diego Padres win 4-3.