Padres vs Brewers Picks and Prediction – 6/7/2025

By: Anthony Allen |

Last Updated: 06/06/2025 at 9:24 PM ET

San Diego Padres at Milwaukee Brewers 06/07/25 - MLB Picks & Predictions
Game Start: 6/7/2025, 11:35 PM UTC
Latest Odds: MIL -117 ; O/U 8.5

Padres vs Brewers Prediction

The San Diego Padres will be returning to American Family Field on Saturday, where they will take on the Milwaukee Brewers. Get the rest of our free MLB picks here! The San Diego Padres are ranked 7th according to ESPN late May rankings. The Padres are 3-2 in the last five games they played against Milwaukee. Stephen Kolek will be San Diego’s starting pitcher on Saturday, he has pitched well against the Brewers not giving up any runs the last two times he faced them. San Diego has the 4th ranked bullpen so far this season. Manny Machado leads the Padres this year with a .317 batting average and 31 RBI. The Padres are 3-2 in their last five games played.

The Milwaukee Brewers sit in 3rd place in the NL Central, as they’ve posted a 34-29 record thus far. The Brewers are ranked 13th according to ESPN as of late May. Jose Quintana is headed to the mound for the Brewers in this game, he is 4-1 with a 2.77 ERA this year. Milwaukee is scoring 4.5 runs per game, while allowing a respectable 3.91 ERA so far. Christian Yelich has found success this season, leading the Brewers with a .237 batting average, 13 home runs and 41 RBI. The Brewers are 4-1 in their last five games played. 

Padres vs Brewers Pick Analysis

The San Diego Padres are 15-16 away from home this season and will be starting Stephen Kolek who is only 1-2 in his last three starts. Kolek has given up 21 hits and 15 runs over his last three starts. The Milwaukee Brewers have been the hotter team scoring more runs than the Padres lately. The Brewers play better at home and starting pitcher Jose Quintana has done well in Milwaukee. The Brewers will do just enough to get a victory at home against San Diego behind some strong pitching. Final Score Prediction, Milwaukee Brewers win 5-4. 

Our Free MLB Pick for Milwaukee Brewers vs San Diego Padres

Milwaukee Brewers -117