Padres vs Brewers Picks and Prediction – 6/7/2025

The San Diego Padres open a three-game series on the road Friday versus the Milwaukee Brewers. San Diego is 35-25 following its 6-5 loss to San Francisco on Wednesday night, snapping a three-game winning streak by the Padres. San Diego has won seven of the last 10. The Padres are second in the National League West, one game behind the first-place Los Angeles Dodgers. Keep up to date with all the MLB action with our MLB picks.

Manny Machado is batting .314 with 70 hits and an on-base percentage of .380 to lead San Diego in the three categories. Fernando Tatis Jr is the leader in home runs with 13, and Gavin Sheets is the leader in RBI with 38. San Diego is batting .249 with a .381 slugging percentage. On Friday, San Diego will send Randy Vasquez to the mound. The right-hander is 3-4 with a 3.99 ERA, 35 Ks, and 30 BBs.

The Milwaukee Brewers improved to 34-29 following Wednesday’s 9-1 victory over the Cincinnati Reds. Isaac Collins hit a three-run homer for Milwaukee while Jackson Chourio and Daz Cameron each hit two-run home runs. Milwaukee has won nine of the last 10. The Brewers are 3rd in the National League Central, five games behind the first-place Chicago Cubs.

Sal Frelick is batting .291 to lead Milwaukee, and Jackson Chourio is the leader in hits with 70, while Rhys Hoskins is the leader in on-base percentage at .364. Christian Yelich is the leader in home runs with 13 and RBI with 41. Milwaukee is batting .239 with a .368 slugging percentage. On Friday, the Brewers will send Chad Patrick to the mound. The right-hander is 3-4 with a 2.97 ERA, 57 Ks, and 18 BBs.

Milwaukee has won 9 of its last 10, while San Diego has lost six of its last 10 played on the road. San Diego starter Randy Vasquez has been hit hard in each of the last two outings, allowing seven runs on 12 hits across 9.2 innings. Milwaukee starter Chad Patrick has had three consecutive strong outings, allowing three runs on 12 hits across 15.1 innings. Final Score Prediction: Milwaukee Brewers win 6-3.