Padres vs Dodgers Picks and Prediction – 6/17/2025

By: David Anicetti |

Last Updated: 06/15/2025 at 7:59 PM ET

San Diego Padres at Los Angeles Dodgers 06/16/25 - MLB Picks & Predictions
Game Start: 6/17/2025, 2:10 AM UTC
Latest Odds: LAD -304 ; O/U 8.5

Padres vs Dodgers Prediction

The San Diego Padres open a four-game series on the road Monday versus National League West rival the Los Angeles Dodgers. San Diego dropped to 38-31 following Saturday’s 8-7 loss to the Arizona Diamondbacks. San Diego has lost three straight and four of the last five. San Diego is third in the National League West, three games behind the first-place Dodgers. Keep up to date with all the MLB action with our MLB predictions.

Manny Machado is batting .318 with 41 RBIs, 83 hits, and an on-base percentage of .379 to lead San Diego in the four categories. Fernando Tatis Jr leads in home runs with 13. San Diego is batting .247 with a .375 slugging percentage. On Monday, San Diego will send Dylan Cease to the mound. The right-hander is 2-5 with a 4.2 ERA, 96 Ks, and 29 BBs.

The Los Angeles Dodgers improved to 42-29 following Saturday’s 11-5 victory over the San Francisco Giants. Shohei Ohtani hit a pair of home runs for Los Angeles, and veteran southpaw Clayton Kershaw threw seven shutout innings, allowing just three hits. The Dodgers have won four of the last six. Los Angeles leads the NL West by one game over the Giants.

Freddie Freeman is batting .338 to lead Los Angeles, while Shohei Ohtani leads in home runs with 25 and hits with 80. Teoscar Hernandez leads in RBI with 50, and Will Smith is the leader in on-base percentage at .419. Los Angeles is batting .264 with a .459 slugging percentage. Los Angeles has not announced its starting pitcher for the opening game of its three-game series at home versus San Diego.

Padres vs Dodgers Pick Analysis

Los Angeles won two out of three over San Diego last week on the road, but the one game the Dodgers lost in the series had Dylan Cease on the mound for San Diego, and the right-hander will start Monday for the Padres. San Diego starting pitcher Cease gave up no runs on three hits across seven Innings last Tuesday in the 11-1 victory over the Dodgers. Final Score Prediction: San Diego Padres win 6-2.

Our Free MLB Pick for Los Angeles Dodgers vs San Diego Padres

San Diego Padres +284