Padres vs Astros Picks and Prediction – 4/19/2025

The San Diego Padres remain on the road Saturday with game two of three in Houston against the Astros. San Diego is rolling to start the year with 15 wins and four losses overall having won for the last five after a 2 run home victory against Chicago in their last outing. Offensively San Diego is dominating this season with a .274 batting average as the Padres have scored 88 runs on 171 hits. The San Diego power is rolling as well with 19 home runs and a .417 team slugging percentage on the year. Stay in the action with our MLB Picks.

Fernando Tatis Jr. is the offensive leader this season for the Padres with a .348 batting average to go along with a team high 6 home runs and 14 RBIs. Manny Machado has a .324 batting average and Gavin Sheets has a .311 batting average. Jackson Merrill has a .378 batting average this year but has played in only 10 games this year.

The Houston Astros will be on their home field Saturday two games below .500 this season having lost three of the last five following a three run road loss to the Cardinals in their last outing. Offensively Houston has been bad this season with a .216 batting average. The Astros have scored just 66 runs on 127 hits this season through 18 games played. The Houston pitching has been mediocre however with a 3.73 team ERA.

Jose Altuve leads Houston this year with a .311 batting averages and is one of 3 players with a team leading 3 homeruns this year. Isaac Paredes and Jeremey Pena are also tied for the team high with 33 homeruns. Yordan Alvarez leads the team with 10 RBIs through 17 games played.

The Padres are on a tear to start the year and will keep it rolling Saturday. Look for the Padres to do the work on both sides of the dish leading to the win in this game. Take San Diego Saturday to continue to roll with a win on the road. Final Score Prediction, San Diego Padres win 6-3.