Padres vs Rockies Picks and Prediction – 5/10/2025

The Colorado Rockies welcome the San Diego Padres on Friday for a weekend series. The Rockies are last in the NL West with just six wins on the season. Colorado is 2-8 over their last ten games and have lost five straight. The Rockies carry a 4-13 home field record. Stay up to date with our expert's MLB Picks. 

Antonio Senzatela will make his 8th start on the mound for the Colorado Rockies. Senzatela is 1-5 on the season with 34.1 innings pitched. Senzatela has 17 strikeouts and carries a 5.51 ERA. Senzatela pitched 5 innings in each of his last two starts. 

The San Diego Padres are 23-13 on the season. The Padres have won six of their last ten games and are riding a two game losing streak. San Diego carries a 9-9 road record. The Padres are averaging 4 runs scored per game with 8.4 hits. 

Randy Vasquez will make his 8th start on the hill for the San Diego Padres. Vasquez is 1-3 on the season with 32.1 innings pitched. Vasquez has 13 strikeouts and carries a 3.90 ERA. Vasquez pitched 5 innings in his last start allowing 6 hits and 1 run. 

Both the San Diego Padres and Colorado Rockies are hoping to snap their current losing streaks. The Padres are road favorites heading into Coors Field. The Colorado Rockies are in jeopardy of losing their sixth straight game. The value is in the total. Final Score Prediction, San Diego Padres win, but the play is on the over 7-5.