San Diego Padres at Colorado Rockies 9/23/22 - MLB Picks & Predictions

The Colorado Rockies host the San Diego Padres for three games starting Sept. 23. Colorado leads the season series 9-7 but lost four games of a five-game series at San Diego to open August. Keep reading below for a preview and prediction for this game then be sure to check out more free MLB previews.

The Padres are 83-66 overall and 43-35 on the road. Against the run line, San Diego is 66-83 overall and 42-36 on the road. The Rockies are 64-86 overall and 40-38 at home. Against the run line, they are 81-69 overall and 43-35 at home.

Sean Manaea is scheduled to start for San Diego. The Padres lefty is 7-9 with a 5.18 ERA over 144 1/3 innings. Manaea has allowed 146 hits and 28 HR, walked 46 and struck out 145.  

Ryan Feltner is set to start for Colorado. He is 3-8 with a 6.05 ERA over 80 1/3 innings. Feltner has given up 87 hits and 14 HR, walked 29 and struck out 72.

Manny Machado leads San Diego with a .296 AVG, 30 HR and 94 RBI. Trent Grisham was 2-for-4 with 2 HR and 3 RBI against Feltner in the Padres’ 13-2 win over the Rockies on Aug. 2.

C.J. Crone leads Colorado with a .267 AVG, 29 HR and 101 RBI. Charlie Blackmon is the Rockies hitter with the most success against Manaea going 3-for-9 including two doubles and a triple.