Padres vs Reds Picks and Prediction – 6/29/2025

The San Diego Padres complete a three-game series on the road Sunday versus the Cincinnati Reds. The Padres dropped to 44-37 following an 8-2 loss to Cincinnati on Friday in the opening game of the series. Nevertheless, San Diego has won four of the last five but trails first-place Los Angeles in the National League West by seven games. Keep up to date with all the MLB action with our MLB picks.

Manny Machado is batting .295 with 47 RBI, 91 hits, and an on-base percentage of .367 to lead San Diego in the four categories. Fernando Tatis Jr leads in home runs with 15. San Diego is batting .246 with a .376 slugging percentage. On Sunday, San Diego will send Stephen Kolek to the mound. The right-hander is 3-3 with a 3.95 ERA, 42 Ks, and 20 BBs.

The Cincinnati Reds improved to 43-39 following Friday’s seven-run victory over the Padres. Nick Martinez entered the 9th inning with a no-hitter but gave up a double to the Padres. Spencer Steer hit three home runs for Cincinnati. The Reds have won four of the last five. Cincinnati trails first-place Chicago in the National League Central by five games. 

TJ Friedl is batting .284 to lead Cincinnati and has a team high on-base percentage of .371. Elly De La Cruz is the leader in home runs with 18, RBI with 56, and hits with 88. Cincinnati is batting .247 with a .403 slugging percentage. On Sunday, the Cincinnati Reds will send Nick Lodolo to the mound. The left-hander is 5-5 with a 3.6 ERA, 80 Ks, and 18 BBs.

San Diego has lost four of its last five played on the road, while Cincinnati has won four of its last five overall, and the Reds are 8-2 in the last 10 played at home. San Diego starter Stephen Kolek has been hit hard in three consecutive outings, allowing 11 runs on 18 hits across 15 innings. Cincinnati starter Nick Lodolo has allowed just three runs on nine hits across 10.1 Innings over the last two outings. Final Score Prediction: Cincinnati Reds win 6-2.