Padres vs Cubs Picks and Prediction – 4/6/2025

The San Diego Padres will be returning to Wrigley Field on Sunday, where they will take on the Chicago Cubs. Get the rest of our free MLB picks here! The San Diego Padres are ranked 10th according to ESPN in the preseason rankings. The Padres are 1-2 in the last three games they played against Chicago. Kyle Hart will be San Diego’s starting pitcher on Sunday, he won his last start against Cleveland. San Diego has the 16th best bullpen in preseason rankings. Jackson Merrill leads the Padres this season with a .429 batting average and 8 RBI.

The Chicago Cubs are ranked 13th according to ESPN in the preseason rankings. Chicago has been very competative playing against San Diego as they are 2-2 in the last four games played at Wrigley Field. Ben Brown is headed to the mound for the Cubs, he struggled allowing ten hits and six runs in his last game pitched. Chicago's bullpen is ranked 20th in preseason rankings. Kyle Tucker leads the Cubs this season with 4 home runs, and 11 RBI.  

The San Diego Padres are 1-3 in their last four games played in Chicago. Padres have not been as good on the road so far this year. The Chicago Cubs will face left-hander Kyle Hart. The Cubs have hit leftys well so far and will get the job done at Wrigley on Sunday. Final Score Prediction, The Chicago Cubs win 4-3.