Padres vs Diamondbacks Picks and Prediction – 6/14/2025

By: Anthony Allen |

Last Updated: 06/12/2025 at 11:24 PM ET

San Diego Padres at Arizona Diamondbacks 06/13/25 - MLB Picks & Predictions
Game Start: 6/14/2025, 1:40 AM UTC
Latest Odds: ARI -125 ; O/U 9.5

Padres vs Diamondbacks Prediction

The San Diego Padres will be returning to Chase Field on Friday, where they will take on the Arizona Diamondbacks. Get the rest of our free MLB picks here! The San Diego Padres are ranked 7th according to ESPN early June rankings. The Padres are 2-3 in the last five games they played against Arizona. Stephen Kolek will be San Diego’s starting pitcher on Friday, he has a record of 3-1 with a 3.00 ERA and has a 1.24 whip this year. San Diego has the 3rd ranked bullpen so far this season. Manny Machado leads the Padres this year with a .320 batting average and 39 RBI. The Padres are 2-3 in their last five games played.

The Arizona Diamondbacks have a 34-34 record and are ranked 19th according to ESPN early June rankings. The Diamondbacks are 1-2 in their last three games played against San Diego. Ryne Nelson will be Arizona's starting pitcher on Friday, he has pitched well in his last two starts against San Diego giving up only four hits and one run. Arizona has the 27th ranked bullpen so far this season. Eugenio Suárez leads the Diamondbacks this year with 19 home runs and 52 RBI. The Diamondbacks are 3-2 in their last five games played. 

Padres vs Diamondbacks Pick Analysis

The San Diego Padres are 2-3 in their last five games played against the Diamondbacks. The series is 5-5 over the last ten games played between these two teams. Ryne Nelson has pitched well against the Padres and will lead the Diamondbacks to a strong start in this matchup. The Diamondbacks will get some timely hitting against San Diego starter Kolek and get the job done at home on Friday night. Final Score Prediction, Arizona Diamondbacks win 6-4. 

Our Free MLB Pick for Arizona Diamondbacks vs San Diego Padres

Arizona Diamondbacks -125