Athletics vs Astros Picks and Prediction – 5/28/2025

By: Thomas Pemberton |

Last Updated: 05/26/2025 at 11:42 PM ET

Sacramento Athletics at Houston Astros 05/27/25 - MLB Picks & Predictions
Game Start: 5/28/2025, 12:10 AM UTC
Latest Odds: HOU -204 ; O/U 7.5

Athletics vs Astros Prediction

The Houston Astros remain at home on Tuesday and welcome in the Oakland Athletics. Houston is 2nd in the AL West with a 28-25 record. The Astros are riding a two game win streak and they carry a 18-10 home field record. Houston is averaging 8.4 hits per game. Stay up to date with our expert's MLB Picks. 

Hunter Brown will make his 11th start on the mound for the Houston Astros. Brown is 6-3 on the season with 61.2 innings pitched. Brown has 71 strikeouts and carries a 2.04 ERA. Brown pitched 5 innings in his last outing allowing 5 runs on 7 hits. The Houston Astros carry a 3.42 team ERA. 

The Oakland Athletics are last in the AL West with a 23-31 record. Oakland is 1-9 over their last ten games and they carry a 14-12 road record. The Athletics are averaging 4.3 runs scored per game. Oakland has 67 home runs on the season. 

JP Sears will make his 11th start on the hill for Oakland. Sears is 4-4 on the season with 54 innings pitched. Sears has 42 strikeouts and carries a 4.00 ERA. Sears pitched 5 innings in his last start allowing 6 runs on 8 hits. 

Athletics vs Astros Pick Analysis

The Houston Astros are seeking their third straight win. The Astros have scored 7 runs over their last two games. Oakland carries a winning road record but they have been a bad team to start the season. The value is in the total. Final Score Prediction, Houston Astros win, but the play is on the under 4-2.

Our Free MLB Pick for Houston Astros vs Sacramento Athletics

UNDER 7.5