Athletics vs Tigers Picks and Prediction – 6/25/2025

By: David Anicetti |

Last Updated: 06/24/2025 at 9:06 PM ET

Sacramento Athletics at Detroit Tigers 06/25/25 - MLB Picks & Predictions
Game Start: 6/25/2025, 10:40 PM UTC
Latest Odds: DET -165 ; O/U 8.5

Athletics vs Tigers Prediction

The Athletics play the second game of a three-game series on the road Wednesday versus the Detroit Tigers. The Athletics are 32-48 following a 3-0 loss to the Cleveland Guardians on Sunday. The A’s lost each of the last two games of a series versus Cleveland after winning the opener. The A’s are last in the American League West, 14 games behind the first-place Houston Astros. Keep up to date with all the MLB action with our MLB picks.

Jacob Wilson is batting .349 with 102 hits and an on-base percentage of .390 to lead the A’s in each of the three categories. Brent Rooker leads in home runs with 15, and Tyler Soderstrom leads the A’s in RBI with 45. The Athletics are batting .252 with a .414 slugging percentage. On Wednesday, the A’s will send Jacob Lopez to the mound. The left-hander is 1-4 with a 4.25 ERA, 49 Ks, and 16 BBs.

The Detroit Tigers improved to 49-30 following Sunday’s 9-3 victory over the Tampa Bay Rays, snapping a three-game losing streak. Riley Greene collected three hits, while Parker Meadows and Wenceel Perez each hit home runs. Detroit leads the American League Central by 8 ½ games over the second-place Guardians.

Riley Greene is batting .291 with 17 home runs, 59 RBI, and 86 hits to lead Detroit in each of the four categories. Gleyber Torres leads in on-base percentage at .386. Detroit is batting .252 with a .419 slugging percentage. On Wednesday, the Detroit Tigers will send Jack Flaherty to the mound. The right-hander is 5-8 with a 4.83 ERA, 93 Ks, and 31 BBs.

Athletics vs Tigers Pick Analysis

The Athletics have won 17 of the last 20 played on the road versus the Tigers. The A's will have a starter on the mound who has been very tough to score on in three straight appearances. Athletics starter Jacob Lopez has pitched well in each of the last three outings, allowing one run on nine hits across 16 innings. Detroit starter Jack Flaherty has struggled in each of the last two outings, allowing 15 runs on 11 hits across 7 innings. Final Score Prediction: Athletics win 6-2.

Our Free MLB Pick for Detroit Tigers vs Sacramento Athletics

Athletics +145