Athletics vs Rockies Picks and Prediction – 4/6/2025

This Saturday, JP Sears and the Athletics face off against Germán Márquez and the Colorado Rockies at Coors Field in the second game of their weekend series. Get our free MLB Picks all season long! The A’s, now 3-5, are coming off a hard-fought 6-3 extra-inning win over Colorado on Friday and are looking to build momentum.

Sears delivered a solid outing in his last appearance and will aim to navigate a tough Rockies lineup in the hitter-friendly altitude of Denver. The Athletics have shown flashes of timely hitting early in the season, and if they can continue to produce with runners in scoring position, Sears should have the support he needs.

The Rockies, sitting at 1-6, are still searching for consistency on both sides of the ball. Márquez will be making his first start of the season and brings plenty of experience, but he’ll need to shake off rust quickly. Colorado’s offense will look to back him up, with pressure mounting after another late-inning collapse.

The Athletics will need to avoid bullpen fatigue following Friday’s 11-inning battle, while Colorado must clean up its defense and string together quality at-bats. This could be a closely contested matchup, with both teams looking to take control early and avoid a late-game scramble.

With JP Sears finding a groove and the Athletics showing clutch hitting late, the Athletics have a solid shot to take a second straight win in Colorado. If Márquez struggles in his first start back, the A’s could capitalize early. Expect another tight game. Final Score Prediction, Athletics win 6-4.