Athletics vs Guardians Picks and Prediction – 7/19/2025

By: David Anicetti |

Last Updated: 07/18/2025 at 8:20 PM ET

Sacramento Athletics at Cleveland Guardians 07/19/25 - MLB Picks & Predictions
Game Start: 7/19/2025, 11:10 PM UTC
Latest Odds: CLE -135 ; O/U 9

Athletics vs Guardians Prediction

The Athletics play the second game of a three-game series on the road Saturday versus the Cleveland Guardians. The Athletics are 41-57 following a 6-3 victory on Sunday over the Toronto Blue Jays. The A’s have won two straight and four of the last six, but trail first-place Houston in the American League West by 16 games. Keep up to date with all the MLB action with our MLB predictions.

Jacob Wilson is batting .332 with 113 hits and an on-base percentage of .375 to lead the Athletics in each of the three categories. Brent Rooker leads in home runs with 20, and Tyler Soderstrom leads in RBI with 56. The Athletics are batting .249 with a .417 slugging percentage. On Saturday, the Athletics will send Luis Severino to the mound. The right-hander is 2-11 with a 5.16 ERA, 81 Ks, and 38 BBs. 

The Cleveland Guardians are 46-49 following Sunday’s 6-5 victory over the Chicago White Sox, in the last game before breaking for five days for the All-Star Game. Cleveland is 18th in ERA and 26th in runs scored. The Guardians have won two straight and six of the last seven. Cleveland trails first-place Detroit in the American League Central by 12 games.

Jose Ramirez is batting .295 with 18 home runs, 50 RBI, and an on-base percentage of .363 to lead Cleveland in each of the four categories. Steven Kwan leads in hits with 103. Cleveland is batting .222 with a .366 slugging percentage. On Saturday, the Cleveland Guardians will send Logan Allen to the mound. The left-hander is 6-7 with a 4.00 ERA, 70 Ks, and 38 BBs.

Athletics vs Guardians Pick Analysis

Athletics starter Luis Severino has been hit hard in three of the last four outings, allowing 18 hits across 17.2 innings. Cleveland starter Logan Allen has had two consecutive solid outings, allowing three runs across 12 innings. Cleveland has won six of its last seven overall, and the Guardians have defeated the Athletics in each of the last seven at home and 12 of the last 14 overall. Final Score Prediction: Cleveland Guardians win 5-3.

Our Free MLB Pick for Cleveland Guardians vs Sacramento Athletics

Cleveland Guardians -135