Athletics vs White Sox Picks and Prediction – 4/17/2025

In Thursday afternoon MLB action, the Athletics will square off against the Chicago White Sox from Guaranteed Rate Field. Be ready for the baseball season with all of our MLB predictions. The Athletics are producing more at the plate in their new Sacramento home ballpark, but their pitching staff ranks near the bottom of the majors with a 4.80 ERA. 1B Tyler Soderstrom leads the team with eight home runs and 17 RBIs. 

Twenty-nine year old left-hander JP Sears (1-2 4.24 ERA) will take the mound for the Athletics in this matchup. Last time out, Sears (4 IP) gave up three runs and struck out seven batters during a 7-6 home loss versus the New York Mets. 

The Chicago White Sox finished last season with 121 losses and are predicted to have the worst record in 2025. Chicago has an improved pitching staff that ranks in the middle of the pack with a 4.10 ERA and has notched a respectable seven quality starts. Talented OF Luis Robert is off to a horrendous start at the plate (.154 avg) and will likely be traded at some point. 

The White Sox will counter with twenty-eight year old righty Davis Martin (1-1 4.24 ERA) in the series finale. In his last start, Martin (6 IP) allowed one run and fanned six batters during an 11-1 home victory versus Boston. 

Chicago outfielders Mike Tauchman (hamstring) and Andrew Benintendi (adductor) are currently on the 10-day injured list. Through 18 games, the Athletics rank 10th in OPS and 12th in runs scored. For the regular season, Chicago ranks 29th in OPS and 29th in runs scored. Take the White Sox to win at home. Final Score Prediction, Chicago White Sox win 5-3.